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Researchers took brain scans and gave memory tests to 188 people who had never taken ecstasy (MDMA). The tests and scans were repeated 18 months later, and differences could be seen in the brains of 59 people who had tried small amounts of ecstasy in the intervening period. On average, those who had newly tried it had taken just six pills.

Club-drug ‘ecstasy’ harmful to first-time users